Companion Diagnostics (동반진단 시약/기기)

August 28, 2015 5:04 PM | Anonymous member

요즘 항암제 개발에 특히 많이 쓰이는것 같은데, 한국에서 이 분야에 전문가를 찾고 계십니다.  혹 아시는 분이 있으신가요? 

예를들어 Iressa (gefitinib)를 투여하는 경우 환자를  찾을때 therascreen® EGFR RGQ PCR Kit을 사용한다 합니다.  혹 이분야를 잘 아시는 분은 연락주십시오. 


The therascreen® EGFR RGQ PCR Kit is a real-time PCR test for the qualitative detection of exon 19 deletions and exon 21 (L858R) substitution mutations of the epidermal growth factor receptor (EGFR) gene in DNA derived from formalin-fixed paraffin-embedded (FFPE) non-small cell lung cancer (NSCLC) tumor tissue. The test is intended to be used to select patients with NSCLC for whom GILOTRIF® (afatinib) or IRESSA® (gefitinib), EGFR tyrosine kinase inhibitors (TKIs), is indicated. Safety and efficacy of GILOTRIF (afatinib) and IRESSA (gefitinib) have not been established in the patients whose tumors have L861Q, G719X, S768I, exon 20 insertions, and T790M mutations, which are also detected by the therascreen EGFR RGQ PCR Kit.

Specimens are processed using the QIAamp® DSP DNA FFPE Tissue Kit for manual sample preparation and the Rotor-Gene Q MDx instrument for automated amplification and detection.
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